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DOI: 10. 1111/j. 1464-5491. 2006. 01868. x
Glycaemic control Assessment Article 3 0742-3071Publishing, alcoholic beverages Diabetic Medicine and2006 consumption D. Ismail et al. DME UK Oxford, content Blackwell Creating Ltd
Cultural consumption of alcohol in adolescents with Type 1 diabetes is definitely associated with increased glucose lability, but not hypoglycaemia
D. Ismail, R. Gebert, P. L. Vuillermin, L. Fraser*, C. M. McDonnell, S. M. DonathвЂ and F. L. Cameron
Department of Endocrinology and Diabetes, Royal Children's Clinic, Melbourne, *Wimmera Base Hospital*, Horsham and вЂ Clinical Epidemiology and Biostatistics Unit, Hoheitsvoll Children's Clinic, Melbourne, Quotes Accepted 15 June 2005
Aims To identify the effects of sociable consumption of alcohol simply by diabetic
teenagers on glycaemic control.
Methods Fourteen (five male) patients aged > 16 years were recruited from the
diabetes clinic at the Royal Kid's Hospital. The continuous sugar monitoring program (CGMS) was attached at a weekend when alcohol consumption was planned for just one night only. For each affected person, the 12-h period via 18. 00 h to 06. 00 h for the night with alcohol consumption (study period) was compared with the same period with non-alcohol intake (control period) either twenty-four h just before or after the alcohol research night. Thus, each subject was his /her own control. Glycaemic outcomes worked out from constant glucose monitoring included mean blood glucose (MBG), percentage of time spent at low blood sugar (CGMS < 4. 0 mmol/l), usual glucose levels (CGMS 4. 0вЂ“10. 0 mmol/ l) and high blood sugar levels (> twelve. 0 mmol/ l) and continuous general net glycaemic action (CONGA). Results The mean number of standard alcohol drinks consumed during the analyze period was 9. 0 for men and six. 3 for females. There was simply no difference in percentage of your time at large and regular glucose levels in the study and control times. During the control period, there was clearly a higher percentage of time with low blood sugar compared with the study period (P < zero. 05). There were an increased amount of glycaemic variation during the examine time when compared with the control period. A conclusion In an out of control, social circumstance, moderately large alcohol consumption simply by adolescents with Type one particular diabetes is apparently associated with increased glycaemic variant, but not with low blood sugar.
Diabet. Mediterranean sea. 23, 830вЂ“833 (2006)
Keywords adolescence, alcohol, glycaemic control Abbreviations CGMS, continuous sugar monitoring program; CONGA, ongoing overall net glycaemic action; MBG, imply blood glucose; RCH, Royal Children's Hospital
Adolescents with Type 1 diabetes frequently engage in risk-taking activities . Among these activities is the cultural
Correspondence to: Dr Fergus Cameron, Mouthpiece Director, Division of Endocrinology and Diabetes, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia. Email: fergus. [email protected] org. au
consumption of alcohol, usually as underage drinkers . Even though the effects of alcohol consumption upon glycaemia have been very well described in a controlled placing [3вЂ“ 6], very little is known about the impact on glucose levels of alcohol consumption simply by adolescents during an ambulant, interpersonal context. The purpose of this job was to make use of continuous glucose monitoring to examine the impact of social drinking on glycaemic control in a group of alcohol-using adolescents.
В© 2006 The Authors.
Journal compilation В© 06\ Diabetes UK. Diabetic Treatments, 23, 830вЂ“833
Sufferers and strategies
This research was approved by the Human Values Research Committee of the Regal Children's Medical center (RCH). That approval was contingent after the fact that the investigators really should not be seen to encourage underage drinking in adolescents. Subsequently, we just approached teenagers who all of us knew had been drinking socially and, inspite of our past counselling, elected to continue to drink...
References: one particular Cameron N, Werther G. Adolescents with diabetes mellitus. In: Menon, RK, Sperling, MA, eds. Pediatric Diabetes. Boston: Kluwer Academic Marketers, 2003: 319вЂ“335. 2 Frey MA, Guthrie B, Lovelandcherry C, Playground PS, Promote CM. Dangerous behaviours and risk in adolescents with IDDM. T Adol Overall health 1997; 20: 38вЂ“45. several Avogaro A, Beltramello G, Gnudi M, Maran A, Valerio A, Miola M et approach. Alcohol intake impairs glucose counterregulation during acute insulin-induced hypoglycaemia in IDDM individuals. Diabetes 1993; 42: 1626вЂ“1634.
4 Kerr D, Macdonald IA, Likas? SR, Tattersal RB. Liquor causes hypoglycaemic unawareness in healthy volunteers and people with type 1 diabetes. Diabetologia 1990; 33: 216вЂ“221. 5 Turner BC, Jenkins E, Kerr D, Sherwin RS, Cavan DA. The result of nighttime alcohol consumption upon next morning glucose control in type 1 diabetes. Diabetes Treatment 2001; 24: 1888вЂ“1893. six Koivisto VIRTUAL ASSISTANT, Tulokas T, Toivonen M, Haapa At the, Pelkonen L. Alcohol with a meal is without adverse effects on postprandial blood sugar homeostasis in diabetic patients. Diabetes Care 93; 16: 1612вЂ“1614. 7 Nationwide Health and Medical Research Authorities. Australian Alcoholic beverages Guidelines: Health problems and Benefits. DS9. Available from: http://www7.health.gov.au/nhmrc/publications/synopses/ds9syn.htm. 8 McDonnell CM, Donath SM, Vidmar SI, Werther GA, Cameron FJ. A novel method of continuous sugar analysis making use of glycaemic variation. Diab Technology Therap 2006; 7: 253вЂ“263. 9 StataCorp. Stata statistical software. Launch 8. zero. College Stop, TX: Stata Corporation, 2003. 10 Kyngas H, Hentinen M, Barlow JH. Adolescents perceptions of physicians, nursing staff, parents and friends: support or burden in compliance with diabetes self-care? J Adv Nurs 1998; twenty seven: 760вЂ“769. 10 Patterson JM, Garwick AW. Coping with persistent illness. In: Werther, GA, Court, JM, eds. Diabetes and the Adolescent. Melbourne: Miranova Publishers 98, 3вЂ“34.
В© 2006 The Authors. Record compilation В© 2006 Diabetes UK. Diabetic Medicine, 23, 830вЂ“833
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